5-Methoxy-1-(3,4,5-trimethoxyphenyl)-1H-indole
نویسندگان
چکیده
The title compound, C(18)H(19)NO(4), was prepared as an indole derivative with possible anti-mitotic properties. The planes of the indole and trimethoxy-phenyl rings make a dihedral angle of 45.35 (5)° with one another. In the crystal, mol-ecules related by a twofold screw axis exhibit arene C-H⋯arene-π inter-actions which are 3.035 (1) Å in length.
منابع مشابه
5-Methoxy-1-[(5-methoxy-1H-indol-2-yl)methyl]-1H-indole
In the title compound, C(19)H(18)N(2)O(2), the two indole ring systems are essentially planar [maximum deviation = 0.015 (2) Å in both indole ring systems] and make a dihedral angle of 72.17 (7)° with each other. In the crystal, the mol-ecules are linked into a zigzag chain along the a axis via N-H⋯O hydrogen bonds.
متن کامل2-(3,4,5-Trimethoxyphenyl)-1H-pyrrolo[2,3-b]pyridine
In the title compound, C(16)H(16)N(2)O(3), the 3,4,5-trimethoxy-phenyl group makes a dihedral angle of 10.04 (7)° toward the 1H-pyrrolo[2,3-b]pyridine system. The crystal structure displays inter-molecular N-H⋯N hydrogen bonds, forming inversion dimers.
متن کامل5-Methoxy-3-[(5-methoxy-1H-indol-3-yl)(phenyl)methyl]-1H-indole
In the title compound, C(25)H(22)N(2)O(2), the indole rings are individually almost planar [with maximum deviations of 0.0116 (19) and 0.0113 (18) Å] and are almost orthogonal to each other, making a dihedral angle of 84.49 (6)°. The benzene ring is inclined at 72.83 (9) and 80.85 (9)° with respect to the indole rings. In the crystal, mol-ecules are linked by N-H⋯O inter-actions into chains run...
متن کامل1-[3-(2-Naphthyl)-5-(3,4,5-trimethoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]ethanone
In the title compound, C(24)H(24)N(2)O(4), the pendant benzene and naphthalene ring systems make dihedral angles of 87.9 (3) and 19.2 (3)°, respectively, with the central pyrazoline ring. In the crystal structure, weak C-H⋯O inter-actions help to establish the packing.
متن کامل5-Methoxy-2-[(5-methoxy-1H-indol-1-yl)carbonyl]-1H-indole
The asymmetric unit of the title compound, C(19)H(16)N(2)O(3), comprises three independent mol-ecules (A, B and C). The inversion-related molecule of A is virtually superimposable upon the other two molecules. In each mol-ecule, there is a twist in the link between the approximately syn carbonyl and amine groups [the N-C-C-O torsion angles range from 19.73 (19) to -21.2 (2)°]. Each mol-ecule ha...
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عنوان ژورنال:
دوره 66 شماره
صفحات -
تاریخ انتشار 2010